For people with poor bones, these 3 things are “triggers”

Does your leg hurt when you walk?
After sitting down and resting for a while, isn’t that better?
And so on the question, the above two have empathy?
In fact, more than 7 into the people will have such a feeling, but these people think that is caused by their overwork, often do not consider the loss of their bone, once their disease is serious, osteoporosis complications appear, it is likely to be very worried!
Also inform everyone from the side, to prevent osteoporosis from small details!

When it comes to osteoporosis, many people don’t realize that their bone health is linked to their eating behaviors.
In particular, the 83-year-old academician who has been studying osteoporosis for 50 years said that osteoporosis is actually caused by their laziness, blind bone raising methods will make your bones more fragile, or suggest that we maintain bones reasonably!

For people with poor bones, these 3 things are “triggers”

1, French fries

For many people, they like to eat French fries, some fast food, biscuits and so on in their daily life. These are processed foods, which contain rich phosphorus. Phosphorus can be absorbed and transformed by the body, but it will also hinder their absorption of calcium.

Many people are because of a large intake of phosphorus containing food, leading to a large loss of calcium, it is easy to induce osteoporosis.
And it’s worth noting that the amount of phosphorus in processed foods can be more than 10 times higher than the amount of calcium.

2, fat

For many people in their daily life, often eat big fish and meat, such a diet habit is actually will lead to the loss of calcium in the body, fat belongs to high fat food, fat is too high, will make the body protein excessive, also gradually cause bone calcium loss!

So, usually as little as possible to eat some fat, light diet!

  1. Donuts

Many people are stuck with their love of donuts.
But donuts are a sweet because of their high sugar content.
If you regularly eat donuts, you will lose bone density and accelerate the loss of calcium from your bones, which will lead to osteoporosis!

These are the three main culprits that cause the loss of calcium in the bones. It is because of them that many people’s health is affected. It is recommended that everyone try to maintain a good diet!

Orthopaedic common sense one: bask in the sun is beneficial to bone?

Many people have heard about the link between sun exposure and bones, but don’t understand why!
In fact, the skin is an important organization for the synthesis of vitamin D. Under the irradiation of ultraviolet light from the sun, it takes cholesterol as raw material to synthesize the skeletal nutrients needed by our human body — vitamin D.

However, a lot of people think suntan, don’t have time to tan, or just sit around the house.
In fact, over time, they will cause a lack of vitamin D, which will also induce osteoporosis!

If you like, bones are stiff, according to a new study

One thing — psoralein

Osteoporosis people, in fact, many people are blind to find some ways to raise bone, looking for, not suitable for their own, after misuse, led to a variety of health problems.
At this time, we are advised to eat psoraletin to increase bone density.

This is also the latest research found that psoralein can indeed help people with poor bones, the first is to retain their own lost calcium, and then promote the body to bone calcium absorption and transformation, improve their calcium utilization!
Psoralein, on the other hand, has been shown to relieve joint pain in people who have lost more than 12 percent of their bone mass.
And for osteoporosis people, can help you to enhance their own resistance at the same time, but also can help you stay away from the complications of osteoporosis!

For people with poor bone, psoraletin can help increase bone density, repair damaged cartilage, and then slow the aging rate of bone and joint, and help people build bones and strengthen bones!

France finds virus that ‘evades nucleic acid tests

A mutated virus that can evade nucleic acid detection was found in France. Eight patients carrying the mutated novel coronavirus that was first discovered showed typical symptoms of infection, but the nucleic acid test (PCR test) of their nasopharyngeal samples was negative, and the nucleic acid test could not detect the new strain.

Why this mutant novel coronavirus can evade nucleic acid detection?
Yu Chuanhua, a professor of epidemiology and health statistics at Wuhan University, told the Health Times: “The new strain carries a total of nine mutations in the S protein and other regions of the virus, so it is impossible to identify two possible cases.
First, the amount of infected virus is not enough to detect or has entered the lungs, resulting in a false negative;
Or it could be that the test is negative or there could be too many mutations to detect.”

The French Directorate General of Health issued a notice

A new variant novel Coronavirus has been discovered at a hospital in the Almor-coeur region of Brittany, France, announced the Directorate General of Health in France.
On February 22nd a cluster of infections was found in a business in Brittany.
Three weeks later, Lani Hospital confirmed 79 patients in the cluster, including eight who carried the novel coronavirus variant, which was first identified.

The 8 patients were negative for nucleic acid tests (PCR) of nasopharyngeal samples, although they had typical symptoms of infection.
Subsequently, after further genetic testing by Pasteur Institute, a new mutant novel coronavirus was found in the sample, and the S protein of the new mutant strain carried 9 mutations in total and other virus regions.

Based on preliminary data, French health authorities have not yet been able to determine whether the new mutant strain is more contagious or will cause more severe infections.
French health authorities are investigating to assess the transmission and severity of the new strain and have reported it to the World Health Organization (WHO).

“COVID-19 is a single-stranded RNA virus, which is more mutable than normal DNA viruses,” Yu told Health Times.
Novel coronavirus infection after the symptoms itself is more complex, and the person’s age, physical conditions, combined with basic diseases and other factors related.”

If the new variant escapes detection, Yu notes, it could spread to other areas without being detected.

Geneticists and endocrinologist at the lille medical center Philip frolg el said in an interview with the French news radio, to determine the variation will be found coronavirus is more contagious and lethal takes longer, today also can’t Brittany found that under the light of strains in its nucleic acid testing is used to inspect a surprise, this need for specialized research.
The novel Coronavirus mutant found in Brittany should be treated with caution.

Yu Chuanhua told Health Times: “Viral mutations have always existed, but they will have some impact on vaccine development.
Vaccine development based on the original strain may not be able to effectively cover the impact of the new strain, so the genetic variation of the new strain should be fully taken into account in vaccine development to avoid the failure of the final vaccine to cover the new mutant strain.”

So COVID-19 needs to be prepared for a longer time.
Yu Chuanhua reminded that the current COVID-19 epidemic situation abroad is still in the state of large-scale epidemic, can not be paralyzed.
In general, any confirmed cases or asymptomatic infections found among people entering the country are unlikely to enter the general community, and the public should not panic.
However, people should still wear masks, wash their hands frequently, ventilate frequently, gather less, and do personal protection consciously.

It took her only eight years to go from being the world’s top supermodel to becoming addicted to drugs and dying of AIDS

Hollywood actress Angelina Jolie,

When I was 23, I acted in a movie.

The main character is a rebellious young girl,

Because the play is so close to my own experience,

Cause her into the play too deep, too long to calm down,

And even stopped acting for six months…

This is an HBO biopic about the trend-setting and pioneering personality of the 1970s and ’80s, Gia Carangi — who became the world’s number one supermodel at 18, then turned into a drug addict and died of AIDS at 26.

Gia had a very bad family of origin. Her parents were always at odds and she often saw them fight.
When she was 11 years old, her parents divorced and her mother left the family alone, which caused huge psychological trauma to Gia who had been very attached to her mother since childhood.

A few years later, Gia met a boy named T.J., and on the first day, she dragged him to get a tattoo and have his picture taken.
At this time she has become a Tingting Yuli big beauty, her face even see more beautiful photographer can not help but praise, the photographer then strongly recommended her from a New York model company interview.

Gia followed the photographers’ advice and traveled from Philadelphia to New York, where the modelling agency’s owners met her and gladly recommended her to photographers, but it was up to her to make it through the audition.

As a result, Gia kept getting rejected after auditioning everywhere, until one day she met Linda, a makeup artist, and with her help she officially entered the modeling circle.

At the same time, Gia’s modeling career seemed to take off, and she became a hot newcomer with a steady stream of offers.

Eventually, she was spotted by a big company and began shooting in the fashion capitals of Rome, Milan and Paris, becoming the first person in the United States to be dubbed a “supermodel.”

At her peak, Gia was earning $10,000 a day, a whopping sum in the late 1970s.
Her fate, however, was like that of the shimmering lake in the afterglow of the setting sun. No matter how brilliant it was, it could not escape its bleak end.

In the 1970s, when life in the fashion world was so extravagant and rotten, many models took a drug called cocaine to maintain their energy.

Gia smoked marijuana at the age of 14 and, after modelling, became a natural crack addict. At first, she may have dabbled with it, but the pressures of work and relationships made her increasingly dependent on drugs.

For example, when her peers teased her about being in a bad mood, Gia turned to cocaine to ease her mood.
Later, the agent died of lung cancer, and in great pain, she turned to heroin to numb herself.

Gia, increasingly addicted to drugs, was on the verge of losing control. During a shooting, she suddenly had a seizure of drug addiction. She immediately left her work and fled the shooting site on a motorcycle, arriving at the home of a drug dealer familiar with her.

But the dealer happened to be out, only a drug addict who was about to inject himself with drugs, driven by the drug addiction, Gia chose to inject drugs into the body.

It was this choice that changed the fate of Gia, who did not know she was infected with HIV.
Later for the cause, she falsely claimed to have given up drugs, with a healthy image to return to the stage to collect money, but the erosion of drugs to her body and mind has let her back to the past.

Drug addiction during the show, secretly injected under the stage.
Within a few months, Gia had spent all her money on drugs. She didn’t even have the energy to work and sometimes fell asleep during the shoot.

Losing her job and no money to buy drugs, Gia sold her body. Drugs made her completely lose her mind, so she was sent to the drug rehabilitation center and went through the torment every day.

There, Gia was no longer a supermodel and no preferential treatment for her beauty, but it also led to a gradual sinking of her heart and the start of drug rehabilitation.

Unfortunately, fate did not give Gia a chance to start over. At the age of 26, she developed AIDS. Her body began to become dehydrated, have fever, develop disease spots on her body, and bleed vaginal blood.

Drugs may bring temporary physical or psychological pleasure and relaxation, but when the feelings slowly fade and disappear, followed by anxiety, depression, irritability and other emotions, these emotions will further aggravate depression.

In order to continue to enjoy the pleasure of relaxation and reduce anxiety, depression, irritability and other emotions, addicts will take the initiative to seek and take drugs, in this vicious circle, the human body will have a serious dependence on drugs, the old disease has not gone to add drug addiction, which is from one extreme to another extreme.

Remember: cherish life, stay away from drugs

Source: Poison Words Poison Words

Anti-drug news newsletter

Anti-drug prevention education lecture into the Tianhe No. 1 Primary School

On March 15th, at the invitation of tianhe first primary school, zhang shengchun, deputy director of guangzhou drug control office, held a lecture on drug prevention education for more than 900 students in the school.
Lectures are held in a main classroom and relayed to all classrooms in the school through a video system.

In the lecture, the wonderful short video played on the big screen recorded the work of anti-drug police and introduced the types and harm of drugs.
The teacher’s vivid and humorous explanation made the students deeply realize the harm of drugs, and improved their ability and consciousness of detecting, preventing and resisting drugs.

After the lecture, the students were very excited and recorded their learning feelings through postscript.
“In the future, I will also resolutely say ‘no’ to drugs. I will not let drugs become a bullet for the anti-drug police,” Shen wrote.

A drug that restrains eosinophils, the killer of asthma

Key words: asthma, eosinophils, IL-5

Clinical scientific research is a kind of medical scientific research with patients as the main research object. The basic starting point is to clarify the important issues in etiology, treatment and prognosis of diseases, so as to achieve the purpose of safeguarding human health.
Therefore, clinical and scientific research have always been complementary to each other.

In China, the incidence of asthma among people over the age of 20 is 4.2 percent, and the number of cases has increased to 45.7 million.
Research into an effective treatment for asthma is urgent.
Next, an example of the literature on eosinophil biomarkers by benralizumab in patients with asthma is presented. Learn, with the author, how he has perfected the synthesis of clinical asthma treatment and research, and how he has published an article quickly and easily.


Airway eosinophilic inflammation is a marker of disease severity in individuals with severe asthma, and eosinophilic driven inflammation is associated with mucus hypersecretion, bronchial hyperresponsiveness, and subepithelial fibrosis in asthma patients.
Current studies have shown that treatments that reduce eosinophilic activity can help relieve symptoms in asthmatic patients with persistent eosinophilic increase.

Among various soluble mediators that regulate airway inflammation in asthma, interleukin 5 (IL-5) mediates eosinophil differentiation, proliferation, activation, and survival.
Benralizumab is a humanized, phosphorylated, anti-IL-5RA monoclonal antibody that selectively reduces eosinophils and basophils by enhancing antibody-dependent cell-mediated cytotoxicity.
So, what about Benralizumab in the clinic?

The results of

  1. Baseline characteristics of patients

The phase I study (MI-CP166) included 14 patients with moderate asthma and the phase IIa study (MI-CP197) included 24 patients with mild to moderate asthma.
Three doses of placebo or Benralizumab were given subcutaneously every 4 weeks.
In both studies, baseline FEV1 and total IgE results were not significantly different between the placebo and Benralizumab treatment groups.
However, baseline FeNO was higher in the Benralizumab group compared to the placebo group.

  1. Markers of eosinophilic inflammation increased in asthmatic patients

Serum EDN concentrations were increased in asthmatic patients in the MI-CP166 and MI-CP197 studies compared with healthy volunteers.
There was a linear correlation between serum baseline EDN concentration and blood eosinophils.

Figure 2 Baseline serum EDN concentrations in asthmatic patients and healthy volunteers in the MI-CP166 and MI-CP197 studies (A,B);
Percentage association between serum EDN concentration and FEV1 predicted by MI-CP166 in asthmatic patients (C);
Eosinophil count (D, F)

  1. Eosinophil granulosin decreased after Benralizumab administration

In the MI-CP166 and MI-CP197 studies, blood eosinophil, serum EDN, and serum ECP concentrations were significantly reduced at all time points, regardless of dose, after Benralizumab treatment (25, 100, or 200 mg) compared to baseline.

Figure 3 Serum eosinophils (A, B), EDN(C, D), and ECP concentrations (E, F) of asthmatic patients in the MI-CP166 and MI-CP197 studies.

  1. Increased IL-5, eotaxin, and eotaxin-2 after Benralizumab administration

Serum IL-5 levels increased in both studies compared to baseline in the Benralizumab group compared to the placebo group.
Serum concentrations of eotaxin-2 / CCL24 were significantly increased in asthmatic patients on day 84 after Benralizumab (200 mg) treatment compared to baseline.
In the placebo group, serum chemokine proteins were not significantly regulated at any time point.

Figure 4 Serum concentrations of IL-5(A, B), eotaxin/CCL11(C, D), and eotaxin-2/CCL24(E, F) in asthmatic patients in two studies.

  1. Benralizumab did not regulate other inflammatory proteins

In the MI-CP166 and MI-CP197 studies, serum concentrations of inflammation-related markers IFN-G, IL-17A, TNF, IL-10, IgE, and CTACK/CCL27 remained unchanged or lower than baseline serum concentrations.

“Healthy” natural anti-inflammatory vegetables, never eat “inflammatory”, anti-inflammatory is better than anti-inflammatory!

Cure a minor ailment and a great one.
Some people think inflammation is “minor disease”, take a bit of medicine good, little know: it is medicine 3 minutes poison, avirulent do not enter medicine.
In fact, inflammation may be out of control after the disease and the whole body, a irreversible.

Before we get into the anti-inflammatory properties of vegetables, let’s take a look at what inflammation is.
Inflammation is the body’s defensive response to a stimulus, characterized by redness, swelling, heat, or pain. It may occur locally or throughout the body.

A new study published recently in the Journal of the American College of Cardiology (JACC) suggests that diet plays a significant role in how much inflammation affects the body.

Diets with a higher pro-inflammatory potential are associated with a higher risk of cardiovascular disease;
Eating an anti-inflammatory diet is an effective strategy to reduce inflammation.

A 32-year study by a team at Harvard University in the US found that diets high in sugar, oil, fat and red meat lead to more inflammation in the body and a 46 per cent increased risk of heart disease.

In response to the findings, many people have questioned why there is no abnormality after eating pro-inflammatory foods that are part of our lives.
In fact, the body itself has a strong immune system, normal inflammation is nothing to be afraid of.
At the same time, you may not realize that you’re taking an anti-inflammatory when you’re taking an inflammatory.

Ginger, garlic and pepper can fight their way out of many vegetables and rank on the list of anti-inflammatory vegetables, because many famous medical books record that their value of medicine and food has been handed down for thousands of years.

In recent years, clinical trials have proven the anti-inflammatory properties of ginger, garlic and chilies, the king of life’s flavorings.

Ginger is old, spicy, anti-inflammatory new development

In a paper titled “Anti-neutrophil Properties of Natural Gingerols in Models of Lupus,” researchers recently published in JCI Insight, a subsidiary issue of the Journal of Clinical Investigation, found that 6-gingerol, a bioactive compound in ginger root, has anti-inflammatory effects and can treat immunological diseases in mice.

Although the study was conducted in a mouse model, the data suggest that 6-gingerol can protect against autoimmune disease, prompting new advances in clinical trials of ginger.

Garlic is a condiment and an anti-inflammatory

Known as the “natural antibiotic” reputation, garlic is rich in anti-inflammatory substances and sulfur compounds, has a strong anti-bacterial and anti-inflammatory effect, to a variety of bacteria, bacillus, fungi and viruses, have inhibition and anti-inflammatory effect, is currently found in the natural plants, one of the strongest antibacterial effect.
The main functional component of garlic is allicin, which is a natural broad-spectrum plant antibiotic with a bactericidal capacity 1/10 of that of penicillin. It can inhibit the growth and reproduction of pathogenic microorganisms, thus alleviating inflammation.
So it’s not surprising that garlic is called a natural antibiotic.
Although studies have been inconsistent, a lot of common sense suggests that garlic may help fight inflammation.

Eating chili peppers may cause irritation, but it may also be anti-inflammatory

Peppers add flavor to delicious foods. The compound that causes this hot taste is called capsaicin.
The amount of capsaicin in a pepper is directly related to the sensation of spiciness, and the more capsaicin, the hotter the pepper.
Capsaicin is an antioxidant that has anti-bacterial, anti-inflammatory and metabolic properties.
It can make your mouth burn, but the pungent compound also has a soothing effect: It triggers a chemical cascade in the gut that may calm the immune system and reduce inflammation.

The researchers studied the phenomenon in mice.
Once inside the gut, the capsaicin molecule binds to a specific receptor and stimulates the release of another compound called arachidonic anthanolamine, which happens to be an endocannabinoid, similar to the active ingredient in cannabis, that binds to cannabinoid receptors in the gut.
The last step in the cascade increased the production of cells that suppress inflammation in mice, and even led to a cure in mouse models with type 1 diabetes, an autoimmune disease.

In conclusion, the level of inflammation in the body is closely related to food, thus affecting the immune ability of the body. Reducing the level of inflammation in the body can significantly improve the immunity of the body.
As the saying goes, “Food is the life of the people, and safety is the first thing to eat.” To make the body less inflammatory, anti-inflammatory vegetables are indispensable!