Recently, I saw several news reports and shared them with you. I hope you can be alert to this situation!
The 42-year-old Ms. Liu found herself ugly in the past six months, her nose became wider, her face wider and her feet larger. She thought she was naturally aging, but she didn’t pay much attention to it, but this change became more and more obvious. After going to the hospital for examination, she realized that it was all because of a pituitary tumor in her head.
For more than a year, Mr. Lin, 36 years old, felt that his appearance became more and more ugly, with protruding jaws, swollen lips, and rough skin. He used to wear shoes of size 40 and now wear size 45, and his snoring sound increased. A week ago, I learned after the hospital examination that the cause of his series of changes was a pituitary tumor in the brain. At present, the doctor has removed the pituitary tumor from the nasal cavity through minimally invasive surgery. After a period of symptomatic treatment, he may restore his previous appearance.
Attentive friends must have discovered that the face suddenly becomes ugly, the hands and feet become thicker, and the skin is rough … These symptoms are all caused by pituitary tumors! ! ! In fact, some people will have such a situation in life, but because there is no concept of the symptoms and harm of pituitary tumors, the best treatment time is missed. Let’s take a look at one type of pituitary tumor-growth hormone secretory pituitary tumor.
What is growth hormone secretory pituitary tumor?
There are many types of pituitary tumors. We have also talked about some different types of pituitary tumors and symptoms before.
The growth hormone-secreting pituitary tumors we are going to talk about today have a higher incidence, accounting for the third place in all pituitary tumors, second only to non-functional pituitary tumors and prolactin-secreting pituitary tumors.
Growth hormone-secreting pituitary tumors are mainly manifested as acromegaly and gigantism, simple gigantism is rare, and acromegaly is secondary to more than half of adulthood. The two patients in the above news are all manifestations of acromegaly.
Why do growth hormone-secreting pituitary tumors cause people to become ugly and have thick hands and feet?
Growth hormone-secreting pituitary tumors cause excessive growth hormone (GH) production in the body. What is growth hormone? It is a single peptide chain protein hormone secreted by eosinophils in the anterior pituitary gland. It is a growth regulator with a wide range of physiological functions.
Excessive long-term growth hormone secretion will lead to abnormal hypertrophy of body type and internal organs, accompanied by abnormal physiological functions. In adolescence, adolescents may present with gigantism, and in adults, acromegaly.
Patients with distal limb hypertrophy caused by growth hormone-secreting pituitary tumors will not only have enlarged hands, feet, nose, lips, wide head and face, high cheekbones, but also hoarse voices, sleep snoring, etc. Patients also have tongue and throat soft tissues It will then become hypertrophic, especially when sleeping at night, it is easy to cause breathing problems.
In addition, the incidence of malignant tumors such as pituitary tumor compression symptoms, diabetes, hypertension, cardiovascular and cerebrovascular diseases, respiratory diseases, and colon cancer will also increase. These metabolic disorders and complications seriously affect the health and quality of life of patients.
How to judge whether your condition is related to acromegaly?
Generally, I can judge based on some unique signs. If in recent years, your shoe size has become larger, your face has changed, your cheekbones have protruded, your forehead has become wider, your voice has become lower, your fingers have become thicker, and your skin has roughened, you can rule out whether you have acromegaly disease.
And more than 95% of patients with acromegaly are caused by growth hormone-secreting pituitary tumors, so the above symptoms should go to the regular hospital neurosurgery. However, because many patients have no other discomforts in the early stage when acromegaly symptoms appear, many people do not treat it as a disease, which delays treatment. Many patients with acromegaly in China have not been diagnosed and have not received treatment. This is mainly because people do n’t understand the disease, they do n’t pay attention to it after symptoms appear, and some people think that face ugliness is not a disease until serious complications such as vision loss, heart disease, cerebrovascular disease, diabetic breathing It is a pity that systemic diseases only came to the clinic and missed the opportunity for early diagnosis and treatment.
How to treat a pituitary tumor with growth hormone secretion?
The purpose of the treatment of growth hormone secreting pituitary tumor is to reduce the level of growth hormone in the blood to normal and reduce the size of the tumor. After successful treatment, many acromegaly symptoms and functions will be reversed or improved (except for the bone changes that have occurred and fixed). The treatment methods include surgery, medication and radiation therapy.
Most growth hormone-secreting pituitary tumors are preferably surgically removed. At present, the most commonly used and patient-welcome is the minimally invasive surgery through the transsphenoidal approach assisted by neuroendoscopy, just like the patient in News 2 above. This type of surgery does not require craniotomy, and uses neuroendoscopy technology to directly reach the site where we need to operate from the nostril, leaving the other parts of the pituitary intact, more accurate, safer, and less postoperative complications.
Introduction to Neurosurgery
The Affiliated Hospital of Northwest University · The Third Surgery Hospital of Xi’an City features “Minimally invasive surgery for craniocerebral spinal cord trauma and tumors, minimally invasive interventional surgery for cerebral and spinal vascular diseases and comprehensive treatment of functional neurosurgical diseases” “Green channel” for the treatment of acute cerebrovascular disease and craniocerebral trauma. There are 50 beds and 19 ICU in the center. ICU has the most advanced detection, monitoring equipment and life support system in the world. The department has become a comprehensive neurosurgery integrating clinical, scientific research, teaching, functional rehabilitation and encephalopathy prevention.